This question occurred to me today as I read something PSIV-related. Alys as well as Rune make comments alluding to knowing Zio, or, at least knowing "of" him in the game. At the beginning of the game in Piata, Alys says, "Zio! That fake magician!" Later in Tonoe, Rune drops a big hint to Chaz and company about not being ready to face Zio. After the Zio fight and Alys gets hurt, we find that Rune's already looking for the psycho wand. I wonder if Rune was planning on facing Zio himself? Maybe he had a premonition of Zio inevitably hurting Alys?
I can't help but wonder, even, if Zio and Rune once had a confrontation of some kind pre-PSIV. Considering that Rune and Alys were once companions while living with Galf, Alys may have heard about Zio through Rune or, perhaps, from Zio's own reputation in Motavia.
What does everyone else think?
Disclaimer: This is all
storyline speculation, I don't think Rune or the other characters are
real. 